{"id":2145,"date":"2023-09-13T17:48:39","date_gmt":"2023-09-13T15:48:39","guid":{"rendered":"https:\/\/www.uni.lu\/lcsb-en\/?page_id=2145"},"modified":"2024-07-22T16:19:02","modified_gmt":"2024-07-22T14:19:02","slug":"the-3rs","status":"publish","type":"page","link":"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/the-3rs\/","title":{"rendered":"The 3Rs"},"content":{"rendered":"<div class=\"section py-0 static\">\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><!-- SecondaryNavigationMirror --><div class=\"js-secondary-nav--sticky wp-block-unilux-blocks-secondary-navigation\" id=\"079cacee-a280-4f42-8b0f-7a37a67d3516\">\n    <nav id=\"secondary-navigation\" role=\"navigation\" aria-label=\"Secondary menu\" class=\"secondary-nav\">\n        <button class=\"secondary-nav__button btn btn-solid--primary w-full\" aria-expanded=\"false\" aria-controls=\"secondary-navigation__list\" title=\"The selected page is 3 Rs\" type=\"button\">\n            <span class=\"btn__name mr-auto\">3 Rs<\/span>\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n                <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\" \/>\n            <\/svg>\n        <\/button>\n\n        <ul id=\"secondary-navigation__list\" class=\"secondary-nav__list\">\n            <li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Overview<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/when-why\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">When and why<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/animal-protection\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Welfare<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/luxembourgish-law\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Luxembourgish Law<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/the-3rs\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link isactived\" aria-current=\"page\">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">3 Rs<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/facilities-2\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Facilities<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/facts-figures\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Facts &amp; Figures<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/case-studies\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Case studies<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/animal-research\/training\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Training<\/span>\n    <\/a>\n<\/li>\n        <\/ul>\n    <\/nav>\n<\/div>\n<!-- end SecondaryNavigationMirror --><\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h1 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"our-research-is-guided-by-the-3rsreplace-reduce-refine\"\n    >\nOur research is guided by the 3Rs:<br>replace, reduce, refine<\/h1>\n\n\n<figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"Mice\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/The-3-Rs_mice.jpg\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/The-3-Rs_mice-300x300.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/The-3-Rs_mice-150x150.jpg 150w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/The-3-Rs_mice-768x768.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/The-3-Rs_mice.jpg 1000w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: cover; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 16\/9; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure>\n\n\n<p>The LCSB applies <a href=\"https:\/\/www.nc3rs.org.uk\/the-3rs\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>the three Rs (3Rs)<\/strong><\/a>, the guiding principles underpinning the humane use of animals in scientific research, in its daily work. Any researcher planning to use animals in their research must first show that there is no available alternative and how the research will be done to minimize numbers and suffering, i.e.:<\/p>\n\n\n\n<ul class=\"ulux-list\">\n<li class=\"ulux-list-item\"><strong>Replace: <\/strong>We aim to use non-animal research methods, such as cell cultures, computer models or studies with human volunteers, wherever possible toavoid the use of animals altogether.<\/li>\n\n\n\n<li class=\"ulux-list-item\"><strong>Reduce: <\/strong>We aim to design our experiments in such a way that only the minimum number of animals is used to answer the given scientific question. This includes obtaining information from fewer animals or gaining more information from the same number of animals. We strive to share and re-analyse data from past experiments to avoid using additional animals.<\/li>\n\n\n\n<li class=\"ulux-list-item\"><strong>Refine:<\/strong> We aim to design and carry out experiments in which animals suffer as little as possible. The impact of an experiment on the animal\u2019s welfare is considered from the planning phase until the end of the procedure. This includes improvements in housing conditions and procedures, which minimize pain and suffering and\/or improve animal welfare.<\/li>\n<\/ul>\n\n\n<figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--scale-down\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"3Rs graphic english\n\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/3R_Graph_english-1.png\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/3R_Graph_english-1-300x82.png 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/3R_Graph_english-1-1024x279.png 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/3R_Graph_english-1-768x209.png 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/3R_Graph_english-1-1536x419.png 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/09\/3R_Graph_english-1.png 1868w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: scale-down; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 32\/9; object-fit: scale-down; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure>\n\n\n<p class=\"has-text-align-center\">The 3Rs. Concept: <a href=\"https:\/\/nc3rs.org.uk\/\" target=\"_blank\" rel=\"noreferrer noopener\">UK National Centre for the Replacement Refinement &amp; Reduction of Animals in Research<\/a><\/p>\n<\/div><\/section>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":39,"featured_media":0,"parent":2052,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"footnotes":""},"field-of-interest":[290],"organisation":[346,202],"authorship":[39],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The 3Rs - LCSB - ±¬ÁϳԹÏÍø I Uni.lu<\/title>\n<meta name=\"description\" content=\"The LCSB applies the three Rs (3Rs), the guiding principles underpinning the humane use of animals in scientific research, in its daily work. 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